Take Home Points:




caffeine_structure Figure 1. Chemical structure of caffeine (1,3,7-trimethylxanthine).

How to Take

Effects on the Brain

Effects on the brain are outlined below.




Side Effects

Effects on the Body

Exercise Performance

Physiological Parameters


Approved as a dietary supplement component under provisions of the Dietary Supplement Health and Education Act of 1994.

Check out this caffeine calculator at caffeine informer to get an estimate of the amount of caffeine safe to consume based on your weight. See table 2 for an estimate of the caffeine content in common foods and drinks.

caffeine_content_food_drink Table 2. Caffeine content of select foods and drinks.

Effects on Disease States

Caffeine & L-theanine

Caffeine and L-theanine can act synergistically to improve alertness and attention. L-theanine can also potentially reverse some of the less favorable physiological effects of caffeine - including increased blood pressure, and reduced flow of oxygenated blood to the head. (Learn more)

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  13. Morgan, A., & Stevens, J. (2010). Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. The Journal of Alternative and Complementary Medicine, 16(7), 753-759.

  14. Smith, A. (2002). Effects of caffeine on human behavior. Food Chem Toxicol, 40(9), 1243-1255.

  15. Burke, T. M., Markwald, R. R., McHill, A. W., Chinoy, E. D., Snider, J. A., Bessman, S. C., . . . Wright, K. P., Jr. (2015). Effects of caffeine on the human circadian clock in vivo and in vitro. Sci Transl Med, 7(305), 305ra146. doi:10.1126/scitranslmed.aac5125

  16. Van Dam, R. M., Pasman, W. J., & Verhoef, P. (2004). Effects of Coffee Consumption on Fasting Blood Glucose and Insulin Concentrations. Diabetes care, 27(12), 2990-2992.

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For informational purposes only. These statements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.